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Small-Cell Carcinoma Transformation of Pulmonary Adenocarcinoma after Osimertinib Treatment: A Case Report

There are various mechanisms underlying the resistance of EGFR-mutant lung adenocarcinoma to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). We herein report a case of pulmonary adenocarcinoma with EGFR mutation (exon 19 deletion and T790M) that acquired resistance to osimer...

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Detalles Bibliográficos
Autores principales: Taniguchi, Yuri, Horiuchi, Hajime, Morikawa, Teppei, Usui, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006630/
https://www.ncbi.nlm.nih.gov/pubmed/29928211
http://dx.doi.org/10.1159/000489603