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How accurate is automated gap filling of metabolic models?

BACKGROUND: Reaction gap filling is a computational technique for proposing the addition of reactions to genome-scale metabolic models to permit those models to run correctly. Gap filling completes what are otherwise incomplete models that lack fully connected metabolic networks. The models are inco...

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Detalles Bibliográficos
Autores principales: Karp, Peter D., Weaver, Daniel, Latendresse, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006690/
https://www.ncbi.nlm.nih.gov/pubmed/29914471
http://dx.doi.org/10.1186/s12918-018-0593-7