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RACIPE: a computational tool for modeling gene regulatory circuits using randomization

BACKGROUND: One of the major challenges in traditional mathematical modeling of gene regulatory circuits is the insufficient knowledge of kinetic parameters. These parameters are often inferred from existing experimental data and/or educated guesses, which can be time-consuming and error-prone, espe...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Jia, Dongya, Feng, Jingchen, Levine, Herbert, Onuchic, José N., Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006707/
https://www.ncbi.nlm.nih.gov/pubmed/29914482
http://dx.doi.org/10.1186/s12918-018-0594-6