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RACIPE: a computational tool for modeling gene regulatory circuits using randomization
BACKGROUND: One of the major challenges in traditional mathematical modeling of gene regulatory circuits is the insufficient knowledge of kinetic parameters. These parameters are often inferred from existing experimental data and/or educated guesses, which can be time-consuming and error-prone, espe...
Autores principales: | Huang, Bin, Jia, Dongya, Feng, Jingchen, Levine, Herbert, Onuchic, José N., Lu, Mingyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006707/ https://www.ncbi.nlm.nih.gov/pubmed/29914482 http://dx.doi.org/10.1186/s12918-018-0594-6 |
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