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High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance

Cluster of differentiation 44 (CD44) is the most common cancer stem cell (CSC) marker and high CD44 expression has been associated with anticancer drug resistance, tumor recurrence, and metastasis. In this study, we aimed to investigate the molecular mechanism by which CD44 and nuclear factor erythr...

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Detalles Bibliográficos
Autores principales: Ryoo, In-geun, Choi, Bo-hyun, Ku, Sae-Kwang, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006726/
https://www.ncbi.nlm.nih.gov/pubmed/29729523
http://dx.doi.org/10.1016/j.redox.2018.04.015