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Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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Detalles Bibliográficos
Autores principales: Vidal-García, Matxalen, Redrado, Sergio, Domingo, M. Pilar, Marquina, Patricia, Colmenarejo, Cristina, Meis, Jacques F., Rezusta, Antonio, Pardo, Julian, Galvez, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006755/
https://www.ncbi.nlm.nih.gov/pubmed/29946309
http://dx.doi.org/10.3389/fmicb.2018.01246