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An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells

BACKGROUND: Gene expression can be influenced by DNA methylation 1) distally, at regulatory elements such as enhancers, as well as 2) proximally, at promoters. Our current understanding of the influence of distal DNA methylation changes on gene expression patterns is incomplete. Here, we characteriz...

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Detalles Bibliográficos
Autores principales: Kennedy, Elizabeth M., Goehring, George N., Nichols, Michael H., Robins, Chloe, Mehta, Divya, Klengel, Torsten, Eskin, Eleazar, Smith, Alicia K., Conneely, Karen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006777/
https://www.ncbi.nlm.nih.gov/pubmed/29914364
http://dx.doi.org/10.1186/s12864-018-4842-3