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An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells
BACKGROUND: Gene expression can be influenced by DNA methylation 1) distally, at regulatory elements such as enhancers, as well as 2) proximally, at promoters. Our current understanding of the influence of distal DNA methylation changes on gene expression patterns is incomplete. Here, we characteriz...
Autores principales: | Kennedy, Elizabeth M., Goehring, George N., Nichols, Michael H., Robins, Chloe, Mehta, Divya, Klengel, Torsten, Eskin, Eleazar, Smith, Alicia K., Conneely, Karen N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006777/ https://www.ncbi.nlm.nih.gov/pubmed/29914364 http://dx.doi.org/10.1186/s12864-018-4842-3 |
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