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Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents

BACKGROUND: Cholangiocarcinoma (CCA), an epithelial malignancy of the biliary tree, is one of the aggressive cancers with poor prognosis and unsatisfactory response to chemotherapy with acquired resistance. NAD(P)H-quinone oxidoreductase 1 (NQO1), an antioxidant/detoxifying enzyme, plays important r...

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Detalles Bibliográficos
Autores principales: Srijiwangsa, Pimradasiri, Ponnikorn, Saranyoo, Na-Bangchang, Kesara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006851/
https://www.ncbi.nlm.nih.gov/pubmed/29914576
http://dx.doi.org/10.1186/s40360-018-0223-4