Cargando…

DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells

The therapeutic benefits offered by 5-fluorouracil (5-FU) are limited because of the acquisition of drug resistance, the main cause of treatment failure and metastasis. The ability of the cancer cells to undergo epithelial-mesenchymal transition (EMT) contributes significantly to cancer metastatic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Kyoung Ah, Ryu, Yea Seong, Piao, Mei Jing, Shilnikova, Kristina, Kang, Hee Kyoung, Yi, Joo Mi, Boulanger, Mathias, Paolillo, Rosa, Bossis, Guillaume, Yoon, Sung Young, Kim, Seong Bong, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006906/
https://www.ncbi.nlm.nih.gov/pubmed/29715584
http://dx.doi.org/10.1016/j.redox.2018.04.020