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Transposable elements generate regulatory novelty in a tissue-specific fashion

BACKGROUND: Transposable elements (TE) are an important source of evolutionary novelty in gene regulation. However, the mechanisms by which TEs contribute to gene expression are largely uncharacterized. RESULTS: Here, we leverage Roadmap and GTEx data to investigate the association of TEs with activ...

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Detalles Bibliográficos
Autores principales: Trizzino, Marco, Kapusta, Aurélie, Brown, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006921/
https://www.ncbi.nlm.nih.gov/pubmed/29914366
http://dx.doi.org/10.1186/s12864-018-4850-3