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Sequential blood meals augment vector infectiousness by promoting Leishmania replication and triggering amplification of metacyclics via a novel retroleptomonad developmental stage

Sand flies, similar to most vectors, take multiple blood meals during their lifetime(1-4). The effect of subsequent blood meals on pathogens developing in the vector, and their impact on disease transmission have never been examined. Here, we show that ingestion of a second uninfected blood meal by...

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Detalles Bibliográficos
Autores principales: Serafim, Tiago D., Coutinho-Abreu, Iliano V., Oliveira, Fabiano, Meneses, Claudio, Kamhawi, Shaden, Valenzuela, Jesus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007031/
https://www.ncbi.nlm.nih.gov/pubmed/29556108
http://dx.doi.org/10.1038/s41564-018-0125-7