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MGMT promoter methylation and 1p/19q co-deletion of surgically resected pulmonary carcinoid and large-cell neuroendocrine carcinoma

BACKGROUND: The response to temozolomide (TMZ) treatment in small-cell lung cancer (SCLC) correlated with O(6)-methylguanine -DNA methyltransferase (MGMT) promoter methylation. 1p/19q co-deletion within oligodendroglioma is a responsive predictor for TMZ. Currently, the status of MGMT promoter methy...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Jiang, Zhiming, Zhang, Gu, Cheng, Qiaoyuan, Lu, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007073/
https://www.ncbi.nlm.nih.gov/pubmed/29914531
http://dx.doi.org/10.1186/s12957-018-1413-7