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A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1

It is now established that cholesterol oxidation products (oxysterols) are involved in several events underlying Alzheimer's disease (AD) pathogenesis. Of note, certain oxysterols cause neuron dysfunction and degeneration but, recently, some of them have been shown also to have neuroprotective...

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Detalles Bibliográficos
Autores principales: Testa, Gabriella, Staurenghi, Erica, Giannelli, Serena, Gargiulo, Simona, Guglielmotto, Michela, Tabaton, Massimo, Tamagno, Elena, Gamba, Paola, Leonarduzzi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007083/
https://www.ncbi.nlm.nih.gov/pubmed/29883958
http://dx.doi.org/10.1016/j.redox.2018.05.009