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C-Linked 8-aryl guanine nucleobase adducts: biological outcomes and utility as fluorescent probes
Aryl radical species derived from enzymatic transformations of aromatic mutagens preferentially react at the 8-site of the guanine (G) nucleobase to afford carbon-linked 8arylG adducts. The resulting lesions possess altered biophysical and genetic coding properties compared to the precursor G nucleo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007177/ https://www.ncbi.nlm.nih.gov/pubmed/29997840 http://dx.doi.org/10.1039/c6sc00053c |