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α7 Nicotinic acetylcholine receptor-mediated anti-inflammatory effect in a chronic migraine rat model via the attenuation of glial cell activation

BACKGROUND: Evidence suggests that the activation of α7 nicotinic acetylcholine receptor (α7nAChR) can greatly decrease the neuroinflammation response. Neuroinflammation plays a pivotal role in the pathogenesis of chronic migraine (CM). Clinical observations also show that nicotine gum induces analg...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Liu, Chaoyang, Jiang, Li, Li, Maolin, Long, Ting, He, Wei, Qin, Guangcheng, Chen, Lixue, Zhou, Jiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007207/
https://www.ncbi.nlm.nih.gov/pubmed/29942148
http://dx.doi.org/10.2147/JPR.S159146