High throughput discovery of protein variants using proteomics informed by transcriptomics

Proteomics informed by transcriptomics (PIT), in which proteomic MS/MS spectra are searched against open reading frames derived from de novo assembled transcripts, can reveal previously unknown translated genomic elements (TGEs). However, determining which TGEs are truly novel, which are variants of...

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Detalles Bibliográficos
Autores principales: Saha, Shyamasree, Matthews, David A, Bessant, Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007231/
https://www.ncbi.nlm.nih.gov/pubmed/29718325
http://dx.doi.org/10.1093/nar/gky295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007231/
https://www.ncbi.nlm.nih.gov/pubmed/29718325
http://dx.doi.org/10.1093/nar/gky295

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