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High throughput discovery of protein variants using proteomics informed by transcriptomics
Proteomics informed by transcriptomics (PIT), in which proteomic MS/MS spectra are searched against open reading frames derived from de novo assembled transcripts, can reveal previously unknown translated genomic elements (TGEs). However, determining which TGEs are truly novel, which are variants of...
Autores principales: | Saha, Shyamasree, Matthews, David A, Bessant, Conrad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007231/ https://www.ncbi.nlm.nih.gov/pubmed/29718325 http://dx.doi.org/10.1093/nar/gky295 |
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