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Lower Renal Function Is Associated With Derangement of 11-β Hydroxysteroid Dehydrogenase in Type 2 Diabetes

CONTEXT: Derangement of 11-β hydroxysteroid dehydrogenase type 1 and type 2 (11β-HSD1 and 11β-HSD2), which regulate intracellular cortisol production, has been suggested in both type 2 diabetes (T2D) and chronic kidney disease (CKD). However, activity of 11β-HSD enzymes in patients with T2D and CKD...

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Detalles Bibliográficos
Autores principales: Gant, Christina Maria, Minovic, Isidor, Binnenmars, Heleen, de Vries, Laura, Kema, Ido, van Beek, André, Navis, Gerjan, Bakker, Stephan, Laverman, Gozewijn Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007243/
https://www.ncbi.nlm.nih.gov/pubmed/29942925
http://dx.doi.org/10.1210/js.2018-00088