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Chikungunya virus evolution following a large 3′UTR deletion results in host-specific molecular changes in protein-coding regions

The 3′untranslated region (UTR) in alphavirus genomes functions in virus replication and plays a role in determining virus host range. However, the molecular evolution of virus UTRs is understudied compared to the evolution of protein-coding regions. Chikungunya virus (CHIKV) has the longest 3′UTR a...

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Detalles Bibliográficos
Autores principales: Morley, Valerie J, Noval, María Gabriela, Chen, Rubing, Weaver, Scott C, Vignuzzi, Marco, Stapleford, Kenneth A, Turner, Paul E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007266/
https://www.ncbi.nlm.nih.gov/pubmed/29942653
http://dx.doi.org/10.1093/ve/vey012