Improving RNA nearest neighbor parameters for helices by going beyond the two-state model

RNA folding free energy change nearest neighbor parameters are widely used to predict folding stabilities of secondary structures. They were determined by linear regression to datasets of optical melting experiments on small model systems. Traditionally, the optical melting experiments are analyzed...

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Detalles Bibliográficos
Autores principales: Spasic, Aleksandar, Berger, Kyle D, Chen, Jonathan L, Seetin, Matthew G, Turner, Douglas H, Mathews, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007268/
https://www.ncbi.nlm.nih.gov/pubmed/29718397
http://dx.doi.org/10.1093/nar/gky270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007268/
https://www.ncbi.nlm.nih.gov/pubmed/29718397
http://dx.doi.org/10.1093/nar/gky270

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