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Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells
RNA 3′ polyadenylation is known to serve diverse purposes in biology, in particular, regulating mRNA stability and translation. Here we determined that, upon exposure to high levels of the intercalating agent ethidium bromide (EtBr), greater than those required to suppress mitochondrial transcriptio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007314/ https://www.ncbi.nlm.nih.gov/pubmed/29518244 http://dx.doi.org/10.1093/nar/gky159 |