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Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells

RNA 3′ polyadenylation is known to serve diverse purposes in biology, in particular, regulating mRNA stability and translation. Here we determined that, upon exposure to high levels of the intercalating agent ethidium bromide (EtBr), greater than those required to suppress mitochondrial transcriptio...

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Detalles Bibliográficos
Autores principales: Toompuu, Marina, Tuomela, Tea, Laine, Pia, Paulin, Lars, Dufour, Eric, Jacobs, Howard T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007314/
https://www.ncbi.nlm.nih.gov/pubmed/29518244
http://dx.doi.org/10.1093/nar/gky159