An origin of the immunogenicity of in vitro transcribed RNA

The emergence of RNA-based therapeutics demands robust and economical methods to produce RNA with few byproducts from aberrant activity. While in vitro transcription using the bacteriophage T7 RNA polymerase is one such popular method, its transcripts are known to display an immune-stimulatory activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Mu, Xin, Greenwald, Emily, Ahmad, Sadeem, Hur, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007322/
https://www.ncbi.nlm.nih.gov/pubmed/29534222
http://dx.doi.org/10.1093/nar/gky177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007322/
https://www.ncbi.nlm.nih.gov/pubmed/29534222
http://dx.doi.org/10.1093/nar/gky177

Ejemplares similares