Easy quantification of template-directed CRISPR/Cas9 editing

Template-directed CRISPR/Cas9 editing is a powerful tool for introducing subtle mutations in genomes. However, the success rate of incorporation of the desired mutations at the target site is difficult to predict and therefore must be empirically determined. Here, we adapted the widely used TIDE met...

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Detalles Bibliográficos
Autores principales: Brinkman, Eva K, Kousholt, Arne N, Harmsen, Tim, Leemans, Christ, Chen, Tao, Jonkers, Jos, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007333/
https://www.ncbi.nlm.nih.gov/pubmed/29538768
http://dx.doi.org/10.1093/nar/gky164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007333/
https://www.ncbi.nlm.nih.gov/pubmed/29538768
http://dx.doi.org/10.1093/nar/gky164

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