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zUMIs - A fast and flexible pipeline to process RNA sequencing data with UMIs
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) experiments typically analyze hundreds or thousands of cells after amplification of the cDNA. The high throughput is made possible by the early introduction of sample-specific bar codes (BCs), and the amplification bias is alleviated by unique molec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007394/ https://www.ncbi.nlm.nih.gov/pubmed/29846586 http://dx.doi.org/10.1093/gigascience/giy059 |