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Two sides of the same coin: A population genetics perspective on lethal mutagenesis and mutational meltdown
The extinction of RNA virus populations upon application of a mutagenic drug is frequently referred to as evidence for the existence of an error threshold, above which the population cannot sustain the mutational load. To explain the extinction process after reaching this threshold, models of lethal...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007402/ https://www.ncbi.nlm.nih.gov/pubmed/29977604 http://dx.doi.org/10.1093/ve/vex004 |