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Quadruplexes in ‘Dicty’: crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome

Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba Dictyostelium discoideum indicates a low number of sequences with G4-forming potential (249–1055). Therefore, D. discoideum is a perfect model organism to investiga...

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Detalles Bibliográficos
Autores principales: Guédin, Aurore, Lin, Linda Yingqi, Armane, Samir, Lacroix, Laurent, Mergny, Jean-Louis, Thore, Stéphane, Yatsunyk, Liliya A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007418/
https://www.ncbi.nlm.nih.gov/pubmed/29718337
http://dx.doi.org/10.1093/nar/gky290