Comparison of Dopamine D(3) and D(2) Receptor Occupancies by a Single Dose of Blonanserin in Healthy Subjects: A Positron Emission Tomography Study With [(11)C]-(+)-PHNO

BACKGROUND: Blockade of D(3) receptor, a member of the dopamine D(2)-like receptor family, has been suggested as a possible medication for schizophrenia. Blonanserin has high affinity in vitro for D(3) as well as D(2) receptors. We investigated whether a single dose of 12 mg blonanserin, which was w...

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Detalles Bibliográficos
Autores principales: Tateno, Amane, Sakayori, Takeshi, Kim, Woo-chan, Honjo, Kazuyoshi, Nakayama, Haruo, Arakawa, Ryosuke, Okubo, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007421/
https://www.ncbi.nlm.nih.gov/pubmed/29346639
http://dx.doi.org/10.1093/ijnp/pyy004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007421/
https://www.ncbi.nlm.nih.gov/pubmed/29346639
http://dx.doi.org/10.1093/ijnp/pyy004

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