Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast

The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA double-stranded breaks. Set2 also confers resistance against the alkylating agent, methyl methanesulfonate (MMS), through an unknown mechanism. Here, we s...

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Detalles Bibliográficos
Autores principales: Lim, Kim Kiat, Nguyen, Thi Thuy Trang, Li, Adelicia Yongling, Yeo, Yee Phan, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007430/
https://www.ncbi.nlm.nih.gov/pubmed/29635344
http://dx.doi.org/10.1093/nar/gky245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007430/
https://www.ncbi.nlm.nih.gov/pubmed/29635344
http://dx.doi.org/10.1093/nar/gky245

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