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Construction and characterization of a new TRAIL soluble form, active at picomolar concentrations

Apoptosis induction has emerged as a treatment option for anticancer therapy. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), a type II transmembrane protein, is a potent and specific pro-apoptotic protein ligand, which activates the extrinsic apoptosis pathway of the cell death rec...

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Detalles Bibliográficos
Autores principales: Melendez, Matias Eliseo, Silva-Oliveira, Renato José, Silva Almeida Vicente, Anna Luiza, Rebolho Batista Arantes, Lidia Maria, Carolina de Carvalho, Ana, Epstein, Alberto Luis, Reis, Rui Manuel, Carvalho, André Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007462/
https://www.ncbi.nlm.nih.gov/pubmed/29930761
http://dx.doi.org/10.18632/oncotarget.25519