Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines

Osteosarcoma (OS) cell lines are widely used in understanding the biological functions of cancer, identification and validation of therapeutic targets, as well as in vitro or in vivo preclinical drug screening. Here we report there is a frequent loss-of-function of polycomb repressive complex 2 (PRC...

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Detalles Bibliográficos
Autores principales: Feng, Helin, Tillman, Heather, Wu, Gang, Davidoff, Andrew M., Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007463/
https://www.ncbi.nlm.nih.gov/pubmed/29930752
http://dx.doi.org/10.18632/oncotarget.25484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007463/
https://www.ncbi.nlm.nih.gov/pubmed/29930752
http://dx.doi.org/10.18632/oncotarget.25484

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