Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arte...

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Detalles Bibliográficos
Autores principales: Pintus, Gianfranco, Giordo, Roberta, Wang, Yushi, Zhu, Wanqu, Kim, Soo Hyuk, Zhang, Li, Ni, Leng, Zhang, Jing, Telljohann, Richard, McGraw, Kimberly R., Monticone, Robert E., Ferris, Chloe, Liu, Lijuan, Wang, Mingyi, Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007470/
https://www.ncbi.nlm.nih.gov/pubmed/29930755
http://dx.doi.org/10.18632/oncotarget.25499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007470/
https://www.ncbi.nlm.nih.gov/pubmed/29930755
http://dx.doi.org/10.18632/oncotarget.25499

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