Cargando…

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pintus, Gianfranco, Giordo, Roberta, Wang, Yushi, Zhu, Wanqu, Kim, Soo Hyuk, Zhang, Li, Ni, Leng, Zhang, Jing, Telljohann, Richard, McGraw, Kimberly R., Monticone, Robert E., Ferris, Chloe, Liu, Lijuan, Wang, Mingyi, Lakatta, Edward G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007470/ https://www.ncbi.nlm.nih.gov/pubmed/29930755 http://dx.doi.org/10.18632/oncotarget.25499

Ejemplares similares

Calorie Restriction Curbs Proinflammation That Accompanies Arterial Aging, Preserving a Youthful Phenotype
por: Wang, Mingyi, et al.
Publicado: (2018)

Increased Aortic Calpain-1 Activity Mediates Age-Associated Angiotensin II Signaling of Vascular Smooth Muscle Cells
por: Jiang, Liqun, et al.
Publicado: (2008)

Inflammatory Role of Milk Fat Globule–Epidermal Growth Factor VIII in Age‐Associated Arterial Remodeling
por: Ni, Leng, et al.
Publicado: (2022)

Proinflammation, profibrosis, and arterial aging
por: Wang, Mingyi, et al.
Publicado: (2020)

Milk Fat Globule Epidermal Growth Factor VIII Fragment Medin in Age-Associated Arterial Adverse Remodeling and Arterial Disease
por: Wang, Mingyi, et al.
Publicado: (2023)

A Local Proinflammatory Signalling Loop Facilitates Adverse Age-Associated Arterial Remodeling
por: Wang, Mingyi, et al.
Publicado: (2011)

Vasorin stimulates malignant progression and angiogenesis in glioma
por: Liang, Weiye, et al.
Publicado: (2019)

Identification of Functional mimotopes of human Vasorin Ectodomain by Biopanning
por: Li, Da, et al.
Publicado: (2018)

TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness
por: Zhu, Wanqu, et al.
Publicado: (2018)

Vasorin deficiency leads to cardiac hypertrophy by targeting MYL7 in young mice
por: Sun, Junming, et al.
Publicado: (2021)

From Vascular Smooth Muscle Cells to Folliculogenesis: What About Vasorin?
por: Bonnet, Anne-Laure, et al.
Publicado: (2018)

Vasorin/ATIA Promotes Cigarette Smoke–Induced Transformation of Human Bronchial Epithelial Cells by Suppressing Autophagy-Mediated Apoptosis
por: Chen, Wenshu, et al.
Publicado: (2019)

Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates
por: Ushakumary, Mereena George, et al.
Publicado: (2019)

Vasorin plays a critical role in vascular smooth muscle cells and arterial functions
por: Louvet, Loïc, et al.
Publicado: (2022)

Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system
por: Liao, Zhiwei, et al.
Publicado: (2022)

SARS-CoV-2 and endothelial cell interaction in COVID-19: molecular perspectives
por: Giordo, Roberta, et al.
Publicado: (2021)

Therapeutic Potential of Resveratrol in COVID-19-Associated Hemostatic Disorders
por: Giordo, Roberta, et al.
Publicado: (2021)

The Utility of Serum Vasorin Levels as a Novel Potential Biomarker for Early Detection of Colon Cancer
por: Aydin, Mehmet, et al.
Publicado: (2022)

Vasorin is a potential serum biomarker and drug target of hepatocarcinoma screened by subtractive-EMSA-SELEX to clinic patient serum
por: Li, Shaohua, et al.
Publicado: (2015)

Exosomal Transfer of Vasorin Expressed in Hepatocellular Carcinoma Cells Promotes Migration of Human Umbilical Vein Endothelial Cells
por: Huang, Aixue, et al.
Publicado: (2015)

Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
por: Djilali, Elias, et al.
Publicado: (2022)

Auto-Antibody Production During Experimental Atherosclerosis in ApoE(-/-) Mice
por: Hutchinson, Mark A., et al.
Publicado: (2021)

Editorial: Arterial Aging and Age-Associated Arterial Diseases
por: Wang, Mingyi, et al.
Publicado: (2018)

Characterization of diverse populations of sinoatrial node cells and their proliferation potential at single nucleus resolution
por: Qu, Jia-Hua, et al.
Publicado: (2022)

Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio)
por: Giordo, Roberta, et al.
Publicado: (2020)

Sialylation of vasorin by ST3Gal1 facilitates TGF‐β1‐mediated tumor angiogenesis and progression
por: Yeo, Hui Ling, et al.
Publicado: (2019)

Role of vasorin, an anti‐apoptotic, anti‐TGF‐β and hypoxia‐induced glycoprotein in the trabecular meshwork cells and glaucoma
por: Choi, Jin A., et al.
Publicado: (2022)

Vasorin Deletion in C57BL/6J Mice Induces Hepatocyte Autophagy through Glycogen-Mediated mTOR Regulation
por: Yang, Lichao, et al.
Publicado: (2022)

Different Redox Response Elicited by Naturally Occurring Antioxidants in Human Endothelial Cells
por: Giordo, Roberta, et al.
Publicado: (2013)

Association between Paraoxonase/Arylesterase Activity of Serum PON-1 Enzyme and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
por: Erre, Gian Luca, et al.
Publicado: (2022)

Discoidin Domain Receptor 2 Regulates AT1R Expression in Angiotensin II-Stimulated Cardiac Fibroblasts via Fibronectin-Dependent Integrin-β1 Signaling
por: Titus, Allen Sam, et al.
Publicado: (2021)

Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
por: Giordo, Roberta, et al.
Publicado: (2021)

Antioxidant Properties of Olive Mill Wastewater Polyphenolic Extracts on Human Endothelial and Vascular Smooth Muscle Cells
por: Posadino, Anna Maria, et al.
Publicado: (2021)

Iloprost Attenuates Oxidative Stress-Dependent Activation of Collagen Synthesis Induced by Sera from Scleroderma Patients in Human Pulmonary Microvascular Endothelial Cells
por: Giordo, Roberta, et al.
Publicado: (2021)

Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications
por: Giordo, Roberta, et al.
Publicado: (2022)

Human Serum Albumin Increases the Stability of Green Tea Catechins in Aqueous Physiological Conditions
por: Zinellu, Angelo, et al.
Publicado: (2015)

Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension
por: Boin, Francesco, et al.
Publicado: (2014)

Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival
por: Posadino, Anna Maria, et al.
Publicado: (2019)

EndMT Regulation by Small RNAs in Diabetes-Associated Fibrotic Conditions: Potential Link With Oxidative Stress
por: Giordo, Roberta, et al.
Publicado: (2021)

Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations
por: Ramli, Iman, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hltbcpvaplhe617gkgt4t28bup