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Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases

Colorectal cancer is characterized by an increase in the utilization of glucose and a diminishment in the oxidation of butyrate, which is a short chain fatty acid. In colorectal cancer cells, butyrate inhibits histone deacetylases to increase the expression of genes that slow the cell cycle and indu...

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Detalles Bibliográficos
Autores principales: Han, Anna, Bennett, Natalie, Ahmed, Bettaieb, Whelan, Jay, Donohoe, Dallas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007476/
https://www.ncbi.nlm.nih.gov/pubmed/29930765
http://dx.doi.org/10.18632/oncotarget.25546