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Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases
Colorectal cancer is characterized by an increase in the utilization of glucose and a diminishment in the oxidation of butyrate, which is a short chain fatty acid. In colorectal cancer cells, butyrate inhibits histone deacetylases to increase the expression of genes that slow the cell cycle and indu...
Autores principales: | Han, Anna, Bennett, Natalie, Ahmed, Bettaieb, Whelan, Jay, Donohoe, Dallas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007476/ https://www.ncbi.nlm.nih.gov/pubmed/29930765 http://dx.doi.org/10.18632/oncotarget.25546 |
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