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An upstream open reading frame (uORF) signals for cellular localization of the virulence factor implicated in pregnancy associated malaria

Plasmodium falciparum, the causative agent of the deadliest form of human malaria, alternates expression of variable antigens, encoded by members of a multi-copy gene family named var. In var2csa, the var gene implicated in pregnancy-associated malaria, translational repression is regulated by a uni...

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Detalles Bibliográficos
Autores principales: Fastman, Yair, Assaraf, Shany, Rose, Miriam, Milrot, Elad, Basore, Katherine, Arasu, B Sivanandam, Desai, Sanjay A, Elbaum, Michael, Dzikowski, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007598/
https://www.ncbi.nlm.nih.gov/pubmed/29554358
http://dx.doi.org/10.1093/nar/gky178