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Sliding of a single lac repressor protein along DNA is tuned by DNA sequence and molecular switching

In any living cell, genome maintenance is carried out by DNA-binding proteins that recognize specific sequences among a vast amount of DNA. This includes fundamental processes such as DNA replication, DNA repair, and gene expression and regulation. Here, we study the mechanism of DNA target search b...

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Detalles Bibliográficos
Autores principales: Tempestini, Alessia, Monico, Carina, Gardini, Lucia, Vanzi, Francesco, Pavone, Francesco S, Capitanio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007606/
https://www.ncbi.nlm.nih.gov/pubmed/29584872
http://dx.doi.org/10.1093/nar/gky208