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Levocarnitine for valproate-induced hyperammonemia in the psychiatric setting: A case series and literature review

INTRODUCTION: Hyperammonemia is a potential adverse effect of valproic acid (VPA) therapy, which is often asymptomatic but can lead to severe, life-threatening encephalopathy. Carnitine deficiency due to VPA is the proposed mechanism for hyperammonemia and the development of VPA-induced hyperammonem...

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Detalles Bibliográficos
Autores principales: Brown, Lauren M., Cupples, Nicole, Moore, Troy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: College of Psychiatric & Neurologic Pharmacists 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007637/
https://www.ncbi.nlm.nih.gov/pubmed/29955560
http://dx.doi.org/10.9740/mhc.2018.05.148