Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4

RNA-binding motif protein 20 (RBM20) is a cardiac splice regulator that adapts cardiac filling via its diverse substrates—including the sarcomeric protein titin. The molecular basis and regulation of RBM20-dependent exon exclusion are largely unknown. In tissue culture experiments, we show that the...

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Detalles Bibliográficos
Autores principales: Dauksaite, Vita, Gotthardt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007684/
https://www.ncbi.nlm.nih.gov/pubmed/29518215
http://dx.doi.org/10.1093/nar/gky165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007684/
https://www.ncbi.nlm.nih.gov/pubmed/29518215
http://dx.doi.org/10.1093/nar/gky165

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