Overexpression of Neuregulin 1 Type III Confers Hippocampal mRNA Alterations and Schizophrenia-Like Behaviors in Mice

Neuregulin 1 (NRG1) is a schizophrenia candidate gene whose protein product is involved in neuronal migration, survival, and synaptic plasticity via production of specific isoforms. Importantly, NRG1 type III (NRG1 III) mRNA is increased in humans inheriting a schizophrenia risk haplotype for the NR...

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Detalles Bibliográficos
Autores principales: Olaya, Juan C, Heusner, Carrie L, Matsumoto, Mitsuyuki, Sinclair, Duncan, Kondo, Mari A, Karl, Tim, Shannon Weickert, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007747/
https://www.ncbi.nlm.nih.gov/pubmed/28981869
http://dx.doi.org/10.1093/schbul/sbx122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007747/
https://www.ncbi.nlm.nih.gov/pubmed/28981869
http://dx.doi.org/10.1093/schbul/sbx122

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