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Overexpression of Neuregulin 1 Type III Confers Hippocampal mRNA Alterations and Schizophrenia-Like Behaviors in Mice
Neuregulin 1 (NRG1) is a schizophrenia candidate gene whose protein product is involved in neuronal migration, survival, and synaptic plasticity via production of specific isoforms. Importantly, NRG1 type III (NRG1 III) mRNA is increased in humans inheriting a schizophrenia risk haplotype for the NR...
Autores principales: | Olaya, Juan C, Heusner, Carrie L, Matsumoto, Mitsuyuki, Sinclair, Duncan, Kondo, Mari A, Karl, Tim, Shannon Weickert, Cynthia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007747/ https://www.ncbi.nlm.nih.gov/pubmed/28981869 http://dx.doi.org/10.1093/schbul/sbx122 |
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