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The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo
Disulfide formation in the mitochondrial intermembrane space is an essential process catalyzed by a disulfide relay machinery. In mammalian cells, the key enzyme in this machinery is the oxidoreductase CHCHD4/Mia40. Here, we determined the in vivo CHCHD4 redox state, which is the major determinant o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007816/ https://www.ncbi.nlm.nih.gov/pubmed/29704824 http://dx.doi.org/10.1016/j.redox.2018.03.014 |