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IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer

Insulin-like growth factor-2 mRNA-binding protein 3 (IMP3) is an oncofetal protein associated with many aggressive cancers and implicated in the function of breast cancer stem cells (CSCs). The mechanisms involved, however, are poorly understood. We observed that IMP3 facilitates the activation of T...

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Detalles Bibliográficos
Autores principales: Samanta, Sanjoy, Guru, Santosh, Elaimy, Ameer L., Amante, John J., Ou, Jianhong, Yu, Jun, Zhu, Lihua J., Mercurio, Arthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007887/
https://www.ncbi.nlm.nih.gov/pubmed/29847788
http://dx.doi.org/10.1016/j.celrep.2018.04.113