Cargando…
IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer
Insulin-like growth factor-2 mRNA-binding protein 3 (IMP3) is an oncofetal protein associated with many aggressive cancers and implicated in the function of breast cancer stem cells (CSCs). The mechanisms involved, however, are poorly understood. We observed that IMP3 facilitates the activation of T...
Autores principales: | Samanta, Sanjoy, Guru, Santosh, Elaimy, Ameer L., Amante, John J., Ou, Jianhong, Yu, Jun, Zhu, Lihua J., Mercurio, Arthur M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007887/ https://www.ncbi.nlm.nih.gov/pubmed/29847788 http://dx.doi.org/10.1016/j.celrep.2018.04.113 |
Ejemplares similares
-
Regulation of IMP3 by EGFR Signaling and Repression by ERβ: Implications for Triple Negative Breast Cancer
por: Samanta, Sanjoy, et al.
Publicado: (2012) -
Feedforward loop between IMP1 and YAP/TAZ promotes tumorigenesis and malignant progression in glioblastoma
por: Yang, Jia, et al.
Publicado: (2023) -
A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP
por: Munro, Trent P., et al.
Publicado: (2006) -
Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge
por: Piersma, Bram, et al.
Publicado: (2015) -
CircCDKN2B-AS1 interacts with IMP3 to stabilize hexokinase 2 mRNA and facilitate cervical squamous cell carcinoma aerobic glycolysis progression
por: Zhang, Yanan, et al.
Publicado: (2020)