High miR-100 expression is associated with aggressive features and modulates TORC1 complex activation in lung carcinoids

PURPOSE: Mammalian target of rapamycin (mTOR) is a promising therapeutic target in advanced lung carcinoid patients. However, the mechanisms of mTOR modulation and of responsiveness to mTOR inhibitors are largely unclear. Our aim was to analyze the expression and functional role of specific miRNAs i...

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Detalles Bibliográficos
Autores principales: Rapa, Ida, Votta, Arianna, Gatti, Gaia, Izzo, Stefania, Buono, Nicola Lo, Giorgio, Elisa, Vatrano, Simona, Napoli, Francesca, Scarpa, Aldo, Scagliotti, Giorgio, Papotti, Mauro, Volante, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007959/
https://www.ncbi.nlm.nih.gov/pubmed/29938004
http://dx.doi.org/10.18632/oncotarget.25541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007959/
https://www.ncbi.nlm.nih.gov/pubmed/29938004
http://dx.doi.org/10.18632/oncotarget.25541

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