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Chimeric antigen receptors that trigger phagocytosis

Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T cells to kill cancer. The success of CAR-T cell therapies highlights the promise of programmed immunity and suggests that applying CAR strategies to other immune cell lineages may be beneficial. Here, we engineered a family o...

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Detalles Bibliográficos
Autores principales: Morrissey, Meghan A, Williamson, Adam P, Steinbach, Adriana M, Roberts, Edward W, Kern, Nadja, Headley, Mark B, Vale, Ronald D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008046/
https://www.ncbi.nlm.nih.gov/pubmed/29862966
http://dx.doi.org/10.7554/eLife.36688