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Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses

Type I interferon (IFN-I) responses are critical for the control of RNA virus infections, however, many viruses, including Dengue (DENV) and Chikungunya (CHIKV) virus, do not directly activate plasmacytoid dendritic cells (pDCs), robust IFN-I producing cells. Herein, we demonstrated that DENV and CH...

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Detalles Bibliográficos
Autores principales: Webster, Brian, Werneke, Scott W, Zafirova, Biljana, This, Sébastien, Coléon, Séverin, Décembre, Elodie, Paidassi, Helena, Bouvier, Isabelle, Joubert, Pierre-Emmanuel, Duffy, Darragh, Walzer, Thierry, Albert, Matthew L, Dreux, Marlène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008049/
https://www.ncbi.nlm.nih.gov/pubmed/29914621
http://dx.doi.org/10.7554/eLife.34273