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Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore

Non-centrosomal microtubule organizing centers (MTOCs) are important for microtubule organization in many cell types. In fission yeast Schizosaccharomyces pombe, the protein Mto1, together with partner protein Mto2 (Mto1/2 complex), recruits the γ-tubulin complex to multiple non-centrosomal MTOCs, i...

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Detalles Bibliográficos
Autores principales: Bao, Xun X, Spanos, Christos, Kojidani, Tomoko, Lynch, Eric M, Rappsilber, Juri, Hiraoka, Yasushi, Haraguchi, Tokuko, Sawin, Kenneth E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008054/
https://www.ncbi.nlm.nih.gov/pubmed/29809148
http://dx.doi.org/10.7554/eLife.33465