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Radiation-enhanced delivery of plasmid DNA to tumors utilizing a novel PEI polyplex

The excitement surrounding the potential of gene therapy has been tempered due to the challenges that have thus far limited its successful implementation in the clinic such as issues regarding stability, transfection efficiency, and toxicity. In this study, low molecular weight linear polyethyleneim...

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Detalles Bibliográficos
Autores principales: Appelbe, Oliver K., Kim, Bieong-Kil, Rymut, Nick, Wang, Jianping, Kron, Stephen J., Yeo, Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008165/
https://www.ncbi.nlm.nih.gov/pubmed/29255216
http://dx.doi.org/10.1038/s41417-017-0004-z