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Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations

BACKGROUND & AIMS: Continual renewal of the intestinal epithelium is dependent on active- and slow-cycling stem cells that are confined to the crypt base. Tight regulation of these stem cell populations maintains homeostasis by balancing proliferation and differentiation to support critical inte...

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Detalles Bibliográficos
Autores principales: Smith, Nicholas R., Swain, John R., Davies, Paige S., Gallagher, Alexandra C., Parappilly, Michael S., Beach, Catherine Z., Streeter, Philip R., Williamson, Ian A., Magness, Scott T., Wong, Melissa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008251/
https://www.ncbi.nlm.nih.gov/pubmed/29928673
http://dx.doi.org/10.1016/j.jcmgh.2018.02.007